Xeris Biopharma Delivers Strong Q1 Growth: Net Income Turns Positive, Recorlev Revenue Almost Doubles


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Xeris Biopharma Delivers Strong Q1 Growth: Net Income Turns Positive, Recorlev Revenue Almost Doubles

Q1 2026 Highlights: Revenue Growth Surges and Net Income Turns Positive

Xeris Biopharma (NASDAQ:XERS) kicked off 2026 with a strong performance, reporting a 43% year-over-year increase in product revenue to $82.45 million for the first quarter. This impressive growth was primarily fueled by Recorlev, which nearly doubled its net revenue to $49.77 million, up 95% compared to the previous year. For the first time in the comparable period, Xeris posted a net income of $2.23 million, a significant turnaround from a $9.22 million net loss in Q1 2025.

Product Q1 2026 Revenue ($ thousands) Q1 2025 Revenue ($ thousands) Change ($ thousands) Change (%)
Recorlev 49,768 25,530 24,238 95%
Gvoke 20,800 20,845 -45 0%
Keveyis 11,886 11,427 459 4%
Product Revenue, Net 82,454 57,802 24,652 43%
Total Revenue 83,127 60,119 23,008 38%

Margin Expansion and Strategic Investments Support Outlook

Xeris’s gross margin improved to 87%, up from 85% a year ago, reflecting a favorable shift in product mix. Despite a 13% bump in R&D expenses (mainly to support the pipeline and the upcoming Phase 3 for XP-8121) and a 21% increase in SG&A (driven by commercial team expansion), Xeris managed to deliver positive operational leverage. Adjusted EBITDA for the quarter reached $15.10 million, nearly tripling the $4.38 million reported in Q1 2025.

Key Metric Q1 2026 Q1 2025
Gross Margin 87% 85%
Net Income (Loss) $2.23M ($9.22M)
Adjusted EBITDA $15.10M $4.38M

Tightened 2026 Guidance and Pipeline Catalysts

With first-quarter performance surpassing expectations, management raised the lower end of its revenue forecast and now expects full-year 2026 revenue between $380 million and $390 million—a growth rate of more than 30% at the midpoint. Looking ahead, additional momentum is expected from the expanded commercial team and the initiation of a Phase 3 trial for XP-8121 later this year, a milestone that could mark a turning point for the pipeline.

Investor Snapshot: Balance Sheet, Shares, and Near-Term Events

As of March 31, 2026, the company reported cash and cash equivalents of $111.75 million, total assets of $392.01 million, and total liabilities of $379.00 million, with 172.6 million shares outstanding at the end of April. Upcoming investor events include appearances at the Craig-Hallum Institutional Investor Conference (May 28) and the Jefferies Global Healthcare Conference (June 3), where management will discuss growth initiatives and future prospects.

Metric Q1 2026 Q4 2025
Cash & Cash Equivalents $111.75M $111.04M
Total Assets $392.01M $383.53M
Total Liabilities $379.00M $369.84M
Total Shares Outstanding 172.64M

Conclusion: Operational Execution and Pipeline Initiatives Could Drive Long-term Value

Xeris’s Q1 results put a spotlight on robust commercial execution, with Recorlev’s outperformance and improved profitability standing out. As the company gears up for key pipeline advancements and maintains a solid financial foundation, investors may want to watch for updates on XP-8121’s progress and continued revenue momentum heading into the second half of the year.


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