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Business Wire 7-May-2026 4:01 PM
Janux Therapeutics, Inc. (NASDAQ:JANX) (Janux), a clinical-stage biopharmaceutical company developing a broad pipeline of novel immunotherapies, today reported financial results for the quarter ended March 31, 2026, and provided a business update.
"Our commitment to advancing a prostate cancer franchise is demonstrated by our continued progress with JANX007, clinical initiation of JANX014, and advancement of JANX013 toward the clinic," said David Campbell, Ph.D., President and CEO of Janux. "Our ongoing clinical study with JANX011 has been designed to support our emerging autoimmune disease opportunity."
BUSINESS HIGHLIGHTS AND RECENT DEVELOPMENTS:
Clinical & Pipeline Progress
Strategic Collaborations
Corporate & Leadership
Upcoming Milestones
FIRST QUARTER 2026 FINANCIAL RESULTS:
About Janux Therapeutics
Janux is a clinical-stage biopharmaceutical company developing a broad pipeline of novel immunotherapies by applying its proprietary technology to its Tumor Activated T Cell Engager (TRACTr), Tumor Activated Immunomodulator (TRACIr), and Adaptive Immune Response Modulator (ARM) platforms.
Janux's lead clinical candidate, JANX007, is a PSMA-targeted TRACTr being investigated in a Phase 1 clinical trial in patients with metastatic castration-resistant prostate cancer (mCRPC). The Company is also advancing additional PSMA-targeted programs, including JANX014, a double-masked PSMA TRACTr being evaluated in a Phase 1 clinical trial, and JANX013, a CD28 co-stimulatory TRACIr designed for combination with JANX007.
Beyond its prostate cancer programs, Janux's pipeline includes JANX011, a CD19-targeted ARM being evaluated in a Phase 1 clinical trial in healthy adult volunteers for potential treatment of autoimmune diseases. Janux continues to generate additional TRACTr, TRACIr, and ARM programs for potential future development.
For more information, please visit www.januxrx.com and follow us on LinkedIn.
Forward-Looking Statements
This news release contains certain forward-looking statements that involve risks and uncertainties that could cause actual results to be materially different from historical results or from any future results expressed or implied by such forward-looking statements. Such forward-looking statements include statements regarding, among other things, Janux's ability to bring new treatments to cancer patients in need, expectations regarding the timing, scope and results of Janux's development activities, including its ongoing and planned preclinical studies and clinical trials, and the potential benefits of Janux's product candidates and platform technologies, expectations regarding the use of Janux's platform technologies to generate novel product candidates and the strength of Janux's balance sheet and the adequacy of cash on hand. Factors that may cause actual results to differ materially include the risk that interim results of a clinical trial are not necessarily indicative of final results and one or more of the clinical outcomes may materially change as patient enrollment continues, following more comprehensive reviews of the data and as more patient data becomes available, including the risk that unconfirmed responses may not ultimately result in confirmed responses to treatment after follow-up evaluations, the risk that compounds that appear promising in early research do not demonstrate safety and/or efficacy in later preclinical studies or clinical trials, the risk that Janux may not obtain approval to market its product candidates, uncertainties associated with performing clinical trials, regulatory filings and applications, risks associated with reliance on third parties to successfully conduct clinical trials, the risks associated with reliance on outside financing to meet capital requirements, and other risks associated with the process of discovering, developing and commercializing drugs that are safe and effective for use as human therapeutics, and in the endeavor of building a business around such drugs. You are urged to consider statements that include the words "may," "will," "would," "could," "should," "believes," "estimates," "projects," "promise," "potential," "expects," "plans," "anticipates," "intends," "continues," "designed," "goal," or the negative of those words or other comparable words to be uncertain and forward-looking. For a further list and description of the risks and uncertainties Janux faces, please refer to Janux's periodic and other filings with the Securities and Exchange Commission, which are available at www.sec.gov. Such forward-looking statements are current only as of the date they are made, and Janux assumes no obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise. All forward-looking statements are qualified in their entirety by this cautionary statement, which is made under the safe harbor provisions of the Private Securities Litigation Reform Act of 1995.
Janux Therapeutics, Inc. |
||||||||
Condensed Balance Sheets |
||||||||
(in thousands) |
||||||||
|
|
March 31, 2026 |
|
December 31, 2025 |
||||
Assets |
|
(unaudited) |
|
|
|
|||
Current assets: |
|
|
|
|
|
|
||
Cash and cash equivalents |
|
$ |
51,828 |
|
|
$ |
52,334 |
|
Accounts receivable, net |
|
|
35,000 |
|
|
|
— |
|
Short-term investments |
|
|
904,558 |
|
|
|
914,233 |
|
Prepaid expenses and other current assets |
|
|
10,663 |
|
|
|
9,320 |
|
Total current assets |
|
|
1,002,049 |
|
|
|
975,887 |
|
Restricted cash |
|
|
816 |
|
|
|
816 |
|
Property and equipment, net |
|
|
3,546 |
|
|
|
3,852 |
|
Operating lease right-of-use assets |
|
|
17,870 |
|
|
|
18,402 |
|
Other long-term assets |
|
|
3,944 |
|
|
|
2,608 |
|
Total assets |
|
$ |
1,028,225 |
|
|
$ |
1,001,565 |
|
|
|
|
|
|
|
|
||
Liabilities and Stockholders' Equity |
|
|
|
|
|
|
||
Current liabilities: |
|
|
|
|
|
|
||
Accounts payable |
|
$ |
3,376 |
|
|
$ |
4,971 |
|
Accrued expenses |
|
|
15,476 |
|
|
|
17,633 |
|
Current portion of deferred revenue |
|
|
37,591 |
|
|
|
— |
|
Current portion of operating lease liabilities |
|
|
2,472 |
|
|
|
2,393 |
|
Total current liabilities |
|
|
58,915 |
|
|
|
24,997 |
|
Deferred revenue, net of current portion |
|
|
8,676 |
|
|
|
— |
|
Operating lease liabilities, net of current portion |
|
|
19,099 |
|
|
|
19,746 |
|
Total liabilities |
|
|
86,690 |
|
|
|
44,743 |
|
Total stockholders' equity |
|
|
941,535 |
|
|
|
956,822 |
|
Total liabilities and stockholders' equity |
|
$ |
1,028,225 |
|
|
$ |
1,001,565 |
|
Janux Therapeutics, Inc. |
||||||||
Unaudited Condensed Statements of Operations and Comprehensive Loss |
||||||||
(in thousands, except share and per share data) |
||||||||
|
|
Three Months Ended March 31, |
|
|||||
|
|
2026 |
|
2025 |
||||
Collaboration revenue |
|
$ |
3,733 |
|
|
$ |
— |
|
Operating expenses: |
|
|
|
|
|
|
||
Research and development |
|
|
26,813 |
|
|
|
25,055 |
|
General and administrative |
|
|
11,133 |
|
|
|
9,842 |
|
Total operating expenses |
|
|
37,946 |
|
|
|
34,897 |
|
Loss from operations |
|
|
(34,213 |
) |
|
|
(34,897 |
) |
Total other income |
|
|
9,852 |
|
|
|
11,389 |
|
Net loss |
|
$ |
(24,361 |
) |
|
$ |
(23,508 |
) |
Other comprehensive gain (loss): |
|
|
|
|
|
|
||
Unrealized gain (loss) on available-for-sale securities, net |
|
|
(3,740 |
) |
|
|
1,593 |
|
Comprehensive loss |
|
$ |
(28,101 |
) |
|
$ |
(21,915 |
) |
Net loss per common share, basic and diluted |
|
$ |
(0.39 |
) |
|
$ |
(0.38 |
) |
Weighted-average shares of common stock outstanding, basic and diluted |
|
|
62,665,717 |
|
|
|
61,791,721 |
|
View source version on businesswire.com: https://www.businesswire.com/news/home/20260507597234/en/
Investors: Chad Rubin Endurance Advisors crubin@enduranceadvisors.com 646.319.3261
Media: Jessica Yingling, Ph.D. Little Dog Communications Inc. jessica@litldog.com 858.344.8091