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Alnylam Pharmaceuticals is a leader in the study of RNA interference (RNAi) therapeutics. RNAi is a naturally occurring biological pathway in cells that enables sequence-specific silencing and regulation of gene expression. Alnylam has five drugs on the market: Onpattro and Amvuttra for hATTR amyloidosis, Givlaari for acute hepatic porphyria, Oxlumo for primary hyperoxaluria type 1, and Leqvio for hypercholesterolemia. It also has several clinical programs across various therapeutic areas: genetic medicines; cardio-metabolic diseases; hepatic infectious diseases, and CNS/ocular diseases. Upfront fees from research partnerships have boosted Alnylam's cash levels, and the company stands to see additional milestones and royalties from drugs commercialized under collaboration partnerships.
Alnylam Pharmaceuticals trades on the NASDAQ stock market under the symbol ALNY.
As of February 25, 2026, ALNY stock price declined to $326.15 with 271,203 million shares trading.
ALNY has a beta of 1.07, meaning it tends to be more sensitive to market movements. ALNY has a correlation of 0.19 to the broad based SPY ETF.
ALNY has a market cap of $43.26 billion. This is considered a Large Cap stock.
Last quarter Alnylam Pharmaceuticals reported $1 billion in Revenue and $1.25 earnings per share. This fell short of revenue expectation by $-53 million and exceeded earnings estimates by $.05.
In the last 3 years, ALNY traded as high as $495.55 and as low as $141.98.
The top ETF exchange traded funds that ALNY belongs to (by Net Assets): VTI, VO, QQQ, VUG, VXF.
ALNY has outperformed the market in the last year with a price return of +31.0% while the SPY ETF gained +17.1%. However, in the short term, ALNY had mixed performance relative to the market. It has underperformed in the last 3 months, returning -24.9% vs +3.8% return in SPY. But in the last 2 weeks, ALNY shares have fared better than the market returning +1.0% compared to SPY 0.0%.
ALNY support price is $324.46 and resistance is $341.24 (based on 1 day standard deviation move). This means that using the most recent 20 day stock volatility and applying a one standard deviation move around the stock's closing price, stastically there is a 67% probability that ALNY shares will trade within this expected range on the day.