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Aprea Therapeutics Inc is a clinical-stage biopharmaceutical company. The group is focused on precision oncology through synthetic lethality. Its pipeline products include ATRN-119, a clinical-stage small molecule ATR inhibitor in development for solid tumor indications. APR-1051, an oral, small-molecule WEE1 inhibitor, recently entered the clinic.
Aprea Therapeutics trades on the NASDAQ stock market under the symbol APRE.
As of December 16, 2025, APRE stock price declined to $0.91 with 20,881 million shares trading.
APRE has a beta of 2.09, meaning it tends to be more sensitive to market movements. APRE has a correlation of 0.30 to the broad based SPY ETF.
APRE has a market cap of $5.75 million. This is considered a Sub-Micro Cap stock.
In the last 3 years, APRE traded as high as $12.00 and as low as $.47.
The top ETF exchange traded funds that APRE belongs to (by Net Assets): VXF.
APRE has underperformed the market in the last year with a price return of -71.5% while the SPY ETF gained +13.6%. APRE has also underperformed the stock market ETF in the last 3 month and 2 week periods returning -39.7% and -17.9%, respectively, while the SPY returned +3.0% and -0.2%, respectively.
APRE support price is $.85 and resistance is $1.00 (based on 1 day standard deviation move). This means that using the most recent 20 day stock volatility and applying a one standard deviation move around the stock's closing price, stastically there is a 67% probability that APRE shares will trade within this expected range on the day.