Ginkgo Bioworks Consortium Secures $22.2M Project for Filovirus Antibody Production Using ProteoNic’s 2G UNic Technology
Major Federal Backing Fuels Push for Faster, More Efficient Antibody Manufacturing
In a significant step toward domestic preparedness for viral outbreaks, Ginkgo Bioworks has licensed ProteoNic’s proprietary 2G UNic® technology for a $22.2 million project aimed at enhancing the manufacturing of monoclonal antibodies (mAbs) against deadly filoviruses such as Ebola and Sudan virus. This effort, funded through BARDA’s Biopharmaceutical Manufacturing Preparedness Consortium (BioMaP-Consortium), gathers a coalition of industry innovators: Ginkgo Bioworks (NYSE: DNA), Advanced BioScience Laboratories (ABL), Isolere Bio by Donaldson, NeuImmune, and ProteoNic.
ProteoNic’s 2G UNic: Increasing Yield and Efficiency for mAbs
ProteoNic’s role centers on deploying its 2G UNic vector and transposon technologies, proven to increase protein expression and productivity in mammalian cell systems. By embedding these tools in the bioproduction workflow, the team aims to dramatically improve manufacturing speed, yield, and scalability—all while lowering overall costs for essential anti-filovirus treatments.
| Consortium Member | Role in Project | Technology/Focus Area |
|---|---|---|
| Ginkgo Bioworks | Consortium Lead, Cell Line Engineering | Cell development & bioautomation |
| ProteoNic | Vector and Transposon Technology Provider | 2G UNic platform for yield and efficiency |
| ABL | Production, Scale-Up, and Purification | Process development & biomanufacturing |
| Isolere Bio by Donaldson | Separation & Purification Innovations | Downstream bioprocessing tools |
| NeuImmune | Therapeutic Innovation | Novel antibody design |
Faster, Scalable, and More Affordable Countermeasures for Public Health Threats
At the core of this consortium is a mission to deliver a more rapid and resilient solution to biologics production—vital for emergency medical countermeasures. ProteoNic’s technology will help maximize the productivity of current manufacturing infrastructure, cutting both time and cost from large-scale bioproduction processes. For the U.S., this marks an important investment in domestic capacity for treatments against filoviruses that can trigger widespread health emergencies.
Next-Gen Biomanufacturing: Sustaining Innovation and Readiness
The BARDA-supported project highlights a larger trend in biologics: integrating premium gene expression and bioprocessing platforms to safeguard global health. ProteoNic’s expanded partnership in therapeutic protein and gene therapy manufacturing further solidifies its position at the forefront of scalable, next-generation biologics solutions. This move is set to deliver not only on speed and efficiency, but also long-term sustainability and biomanufacturing resilience in the face of emerging viral threats.
Key Takeaway: Federal-Backed Innovation Could Redefine U.S. Preparedness
The $22.2 million BARDA award signals growing federal commitment to public health security and biotechnology infrastructure. Investors and stakeholders may want to track further developments from this consortium as advancements in technology and regulatory support could have far-reaching impacts on the broader sector—and on readiness for the next infectious disease crisis.
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