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Spyre Therapeutics (SYRE)'s 30-day implied volatility (IV30) was 71.1% at the close on November 2, 2026, down from 72.7% the day before, against a 52-week range of 45.4% to 114.2%. Its 20-day historical volatility was 63.6%.

Key numbers
  • 30-day implied volatility (IV30): 71.1%
  • IV30 52-week range: 45.4% to 114.2% (median 65.3%)
  • Historical volatility: 20-day 63.6%, 1-year 62.9%
  • Implied move by the nearest expiration: ±4.7%

Data as of November 2, 2026.

SYRE Implied Volatility (IV) vs Historical Volatility (HV)

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