Upstream Bio (UPB)'s 30-day implied volatility (IV30) was 98.4% at the close on November 6, 2026, up from 93.7% the day before, against a 52-week range of 48.4% to 269.2%. Its 20-day historical volatility was 119.4%.

Key numbers

30-day implied volatility (IV30): 98.4%
IV30 52-week range: 48.4% to 269.2% (median 72.3%)
Historical volatility: 20-day 119.4%, 1-year 77.4%
Implied move by the nearest expiration: ±6.0%

Data as of November 6, 2026.

UPB Implied Volatility (IV) vs Historical Volatility (HV)

Name: UPB Implied Volatility
Creator: Market Chameleon