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Unusual Option Volume

UPB Upstream Bio14.70-13.11 (-47.1%)

After Hours:0.00-14.70 (-100.0%)

Upstream Bio trades 2,331 contracts. The company has the following event: Webcast to Report Top-Line Results from the Phase 2 VALIANT Trial of Verekitug in Patients with Severe Asthma on Feb 11, 2026. News: Upstream Bio Reports Positive Top-line Results from the Phase 2 VALIANT Trial of Verekitug for the Treatment of Severe Asthma
UPB #UpstreamBio stock declines -29.9% in premarket,

Premarket Decliner

UPB Upstream Bio27.81+1.69+6.5%

Premarket:19.49-8.32 (-29.9%)

Upstream Bio Reports Positive Top-line Results from the Phase 2 VALIANT Trial of Verekitug for the Treatment of Severe Asthma

Globe NewswireWed, 11-Feb 6:00 AM

UPB #UpstreamBio stock increases 15.1% after hours.

After Hours Gainer

UPB Upstream Bio27.81+1.69+6.5%

After Hours:32.00+4.19 (+15.1%)

Upstream Bio to Host Webcast to Report Top-Line Results from the Phase 2 VALIANT Trial of Verekitug in Patients with Severe Asthma

Globe NewswireTue, 10-Feb 6:00 PM

UPB #UpstreamBio stock increases 11.5% after hours.

After Hours Gainer

UPB Upstream Bio27.81+1.69+6.5%

After Hours:31.00+3.19 (+11.5%)

Upstream Bio to Host Webcast to Report Top-Line Results from the Phase 2 VALIANT Trial of Verekitug in Patients with Severe Asthma

Globe NewswireTue, 10-Feb 6:00 PM

Unusual Option Volume

UPB Upstream Bio27.59+1.47 (+5.6%)

Upstream Bio trades 3,384 contracts.
Unusual Option Volume

UPB Upstream Bio31.00-1.50 (-4.6%)

Upstream Bio trades 4,303 contracts.
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