Oracle Teams with AMD for 50,000-GPU Supercluster—A Major Leap in AI Scale and Open Cloud Infrastructure
First-of-Its-Kind Supercluster with 50,000 AMD Instinct MI450 GPUs to Debut in 2026
Oracle and AMD are pushing the boundaries of AI infrastructure with a bold plan: launching the first publicly available AI supercluster running on 50,000 AMD Instinct MI450 Series GPUs, starting Q3 2026. This joint venture marks the latest milestone in a multi-generation collaboration between the two tech giants, directly responding to surging demand for more robust, scalable, and energy-efficient AI solutions.
Unprecedented Performance: Why 50,000 GPUs Matter for Next-Gen AI
As AI workloads rapidly outgrow traditional clusters, the need for supercharged compute solutions has never been more apparent. Each MI450 GPU offers up to 432 GB of next-generation HBM4 memory and an eye-popping 20 TB/s of memory bandwidth, supporting in-memory models up to 50% larger than prior generations. This leap means data scientists and engineers can tackle complex AI tasks with less partitioning and faster results.
| Key Metric | AMD Instinct MI450 Series GPU | Improvement Over Previous Gen |
|---|---|---|
| Memory per GPU | 432 GB HBM4 | +50% |
| Memory Bandwidth | 20 TB/s | Substantial Increase |
| Supercluster Launch | Q3 2026 | First-of-its-kind |
| Initial Deployment | 50,000 GPUs | N/A |
Technical Indicators Point to Leadership in Scale, Flexibility, and Security
This rollout is more than just a big hardware deployment. It leverages a vertically-integrated, rack-scale architecture using AMD’s "Helios" design—complete with liquid-cooled racks and advanced networking technology. Notably, Oracle will introduce next-generation AMD EPYC CPUs (code named “Venice”) and programmable AMD Pensando DPU-based networking, delivering secure, low-latency, and energy-efficient connectivity for multi-trillion-parameter AI models.
Key features include open-source AMD ROCm software, innovative UALink fabric for fast interconnectivity, and virtualization capabilities to allocate resources dynamically based on workload needs. Combined, these offer an open, secure, and highly flexible environment for AI development, suitable for a new era where scalability and cost-effectiveness are non-negotiable.
Cloud Flexibility: OCI Compute with MI355X Powers Further Expansion
Alongside the headline-grabbing MI450 supercluster, Oracle will make available its zettascale OCI Supercluster, powered by up to 131,072 AMD Instinct MI355X GPUs. These solutions provide cloud customers with even more options for open-source, high-performance AI workloads. Customers will benefit from enhanced partitioning, rapid provisioning, and support for today’s most demanding generative AI and HPC needs.
| Deployment | GPU Model | Total GPU Count |
|---|---|---|
| Supercluster (2026) | MI450 Series | 50,000 (and expanding) |
| Zettascale OCI Supercluster | MI355X | 131,072 |
Conclusion: Major Step for Open, Secure AI at Scale
Oracle and AMD’s expanded partnership marks a significant turning point in the global race to deliver AI at massive scale, with openness, flexibility, and security at its core. As hyperscale demand accelerates and enterprises hunt for next-gen solutions, this supercluster initiative is set to redefine what's possible for cloud AI infrastructure—while leaving the door open for innovation across the broader AI ecosystem.
Investors and technology leaders will be watching closely as deployment draws near. The sheer scale and technical ambition behind the Oracle-AMD supercluster could set new benchmarks for the industry—and reset expectations for the pace of AI-driven innovation.
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