Karyopharm Therapeutics (KPTI)'s 30-day implied volatility (IV30) was 202.2% at the close on November 10, 2026, up from 196.5% the day before, against a 52-week range of 61.5% to 400.0%. Its 20-day historical volatility was 273.8%.

Key numbers

30-day implied volatility (IV30): 202.2%
IV30 52-week range: 61.5% to 400.0% (median 107.3%)
Historical volatility: 20-day 273.8%, 1-year 130.6%
Implied move by the nearest expiration: ±12.4%

Data as of November 10, 2026.

KPTI Implied Volatility (IV) vs Historical Volatility (HV)

Name: KPTI Implied Volatility
Creator: Market Chameleon