Option chain for Karyopharm Therapeutics (KPTI): calls and puts for every expiration and strike, with quotes, volume, open interest, implied volatility and greeks. As of Oct 20, 2026, KPTI had 7 option expirations, from Nov 20, 2026 to Jan 19, 2029, and 132 contracts traded that day. The nearest expiration, Nov 20, 2026, had an at-the-money implied volatility of 218.4% (-3% on the day) and 5 contracts traded; the busiest was Dec 18, 2026, with 65.

For the latest figures, see KPTI options overview.

Key numbers

Expirations: at-the-money implied volatility, change on the day, volume

Nov 20, 2026 (31 days): ATM IV 218.4% (-3%), volume 5
Dec 18, 2026 (59 days): ATM IV 134.1% (-22%), volume 65
Jan 15, 2027 (87 days): ATM IV 212.5% (+43%), volume 0
Feb 19, 2027 (122 days): ATM IV 134.1% (-31%), volume 0
May 21, 2027 (213 days): ATM IV 184.6% (-6%), volume 1
Jan 21, 2028 (458 days): ATM IV 188.0% (-22%), volume 61
Jan 19, 2029 (822 days): ATM IV 153.2% (+1%), volume 0

Data as of October 20, 2026.

KPTI Option Chain

Detailed and comprehensive option chain for each expiration listed for KPTI. Includes volume, open interest, implied volatility, and bid/ask for each strike. Investigate further by clicking on a strike and seeing trade activity, volatility movement, and yesterday's closing values. Use the built-in options profit calculator to see the profit or loss of any KPTI options strategy.

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