LYEL Stock Summary and Trading Ideas (Lyell Immunopharma | NASDAQ:LYEL)

Lyell Immunopharma Inc s a late-stage clinical cell therapy company advancing a pipeline of proprietary next-generation autologous chimeric antigen receptor (CAR) T-cell product candidates for patients with hematologic malignancies and solid tumors. The Company's product candidate, rondecabtagene autoleucel (ronde-cel, also known as LYL314), is an autologous dual-targeting CD19/CD20 CAR T-cell therapy in development for large B-cell lymphoma (LBCL). The Company has recently acquired exclusive rights outside of mainland China, Hong Kong, Macau and Taiwan, to a novel guanylyl cyclase C (GCC)-targeted CAR T-cell product candidate in early clinical development for refractory metastatic colorectal cancer (mCRC) and other GCC-expressing cancers.

Lyell Immunopharma trades on the NASDAQ stock market under the symbol LYEL.

As of April 8, 2026, LYEL stock price climbed to $22.31 with 13,342 million shares trading.

LYEL has a beta of 1.51, meaning it tends to be more sensitive to market movements. LYEL has a correlation of 0.08 to the broad based SPY ETF.

LYEL has a market cap of $519.98 million. This is considered a Small Cap stock.

Last quarter Lyell Immunopharma reported $6,000 in Revenue and -$7.68 earnings per share. This fell short of revenue expectation by $-14,330 and missed earnings estimates by -$5.48.

In the last 3 years, LYEL traded as high as $79.40 and as low as $7.65.

The top ETF exchange traded funds that LYEL belongs to (by Net Assets): VTI, VXF, SCHA, IBB, VHT.

LYEL has outperformed the market in the last year with a price return of +149.8% while the SPY ETF gained +35.0%. However, in the short term, LYEL had mixed performance relative to the market. It has underperformed in the last 3 months, returning -10.9% vs -2.0% return in SPY. But in the last 2 weeks, LYEL shares have fared better than the market returning +13.2% compared to SPY +3.2%.

LYEL support price is $20.44 and resistance is $23.13 (based on 1 day standard deviation move). This means that using the most recent 20 day stock volatility and applying a one standard deviation move around the stock's closing price, stastically there is a 67% probability that LYEL shares will trade within this expected range on the day.